March 19, 2024
Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay.

Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay.

The proximal promoter area of many human growth-related genes comprises a polypurine/polypyrimidine tract that serves as a number of binding websites for Sp1 or different transcription elements. These tracts typically